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Dynamic Markers

Aim of project

There are three purposes of the DM project:

Description

Cells in suspension can be labelled with super-paramagnetic crystals which are linked to the cell surface by suitable antibodies.

A major application of this technique is the sorting of the marked cells due to external DC fields (1).

Still the DM techniques seem to be unknown (patents appl. (2, 3)).

One of the objectives of the new DM technique is an increased registration selectivity of marked objects.

By applying or not applying dynamic magnetic fields to the labelled objects, the observer can either move or not move the marked objects in particular ways. Therefore, in connection with these special external fields the super-paramagnetic nm-particles become Dynamic Markers enabling the marked objects to perform controlled movements. These movements can be viewed under the microscope. This allows to observe single, dynamically marked objects among a large number of unmarked objects, an aspect important in cancer research.

Another aim of the DM is to utilise the special movement abilities and the very fast speeds attainable by magnetically labelled particles. These aspects can be useful in directing antibodies or vesicles containing drugs for target orientated drug supply.

  1. www.MiltenyiBiotec.com
  2. Dynamic Marker
  3. A non-invasive procedure and an apparatus for determining the haemoglobin content of blood

Project Type

Exploratory Award

Partners

  1. www.MiltenyiBiotec.com
  2. Dynamic Marker
  3. A non-invasive procedure and an apparatus for determining the haemoglobin content of blood

Project Type

Exploratory Award

Partners

  1. SME Stetter Elektronik (DE)
  2. SME Feldkraft (DK)
  3. Prof. Wolf, Technische Universität München (DE)
  4. Prof. Weitschies, Universität Greifswald (DE)
  5. Prof. Miszalski, Polnish Academy of Sciences (P)
  6. Biophysical Institute, Universtity of Lodz (P)

etc.

Contact:

Martin Koch
Hojbovej 11
DK – 2500 Copenhagen
Tel: 0045 36139312
Fax: 0045 36139314
E-Mail: mko@mail.tele.dk
info@stetter-elektronik.de